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The French pharmaceutical company is developing a new oral small molecule targeting the lysosomal compartment of cancer cells, including cancer stem cells.
In vitro data confirmed the anti-cancer agent action on many tumor types (colon carcinoma,... more
A French clinical research team has developped an innovative paediatric treatment for autistic disorders coming from a specific enzym deficiency. The team is represented by a Technology Transfer Office (TTO) which... more
A French clinical research team has developed an innovative treatment for paediatric epileptic seizures coming from a vitamin-sensitive effect. This research team is represented by a Technology Transfer Office... more
Ukrainian research and development clinical institution was established in 1920. Now it is the leading organization in the country which conducts cancer research on the basic, translational and clinical... more
Background: The company was founded some years ago as a spin-off from a Southern German university. The company offers a solution for structured medical reporting and clinical guidance. The first platform was launched... more
24/7 that allow having a clear image of the exact ongoing condition. Although some systems are available for use in clinical settings, there is not yet an option for parents to monitor signs reliably at home.... more
Molecular diagnostics is important, among others, in the field of health, food safety and environment. In the clinical field it provides a reliable aid for deision-making in treatment of patients.
The problem of... more
A university origin SME in northern Sweden active in the field of inflammatory research offers a new pre-clinical model, the N-IF mouse, for testing new anti-fibrotic and anti-inflammatory drugs.
The N-IF mouse... more
of cancer and other complex diseases with an important genetic background. However, the in vivo delivery of oligonucleotides (OGN) has precluded the clinical use of gene-based therapies mainly due to its vulnerability... more
Wnt signalling is implicated, such as stonach, liver and pancreatic cancer. Testing on this molecule shows that it displays anti-proliferative activity in pre-clinical in vivo models, has a favourable pharmacokinetic... more
) orphan disease space—the company’s therapeutic focus.
The company’s pipeline consists of clinical-stage assets for Huntington’s disease and Adrenoleukodystrophy, as well as preclinical-stage assets for Adrenomyeloneuropathy,... more
oral and ocular application. They published over a hundred articles in high-impact scientific journals.
Partners are sought to participate with the finalisation of the pre-clinical and/or clinical... more
research centers and 16 production sites this French company has a global reach. With 33 drug candidates in clinical development, they are specialized in 5 major axes: cardiovascular diseases, diabetes, cancers,... more
low molecular weight clinical candidate showed increased efficacy and potency on angiogenesis when compared to reference compounds or vehicles. Therapies based on the drug candidate are expected to provide significant... more
quality assurance laboratories including cell biology and molecular biology laboratories. Company’s customers include hospitals, biotech and pharmaceutical companies conducting cell therapy-based clinical trials.
has confirmed the efficacy of the treatment protocol used to improve patients’ clinical situation. Results show that the interference arising from having experienced stressing events is significantly reduced in... more
indication. Until now, only a few materials are under research investigation. Moreover, such results haven't reached the clinical milestone yet because of an obvious major issue : it is strongly difficult to set... more
performing pre-clinical studies where both acute toxicity and efficacy tests were cleared confirming therefore the compound therapeutic effects that are at least twice more efficient than the drugs actually on... more
numerous caspase-1 inhibitors have been synthesized, no inhibitor has passed the clinical trial, probably because of the covalent mechanism of action and the consequent unwanted off-target interactions.
The research... more
therapeutic interventions with the latest digital solutions in a secure, user friendly web-based environment. It uses a blended approach where therapeutic interventions are supported by online tools and clinical... more