Enzymatic/microbial platform technology offers solutions for biocatalysis for chemical, food, pharma and materials industry
German-Sino SME provides all-in-one R&D /commercialisation services and biocatalytic solutions via an enzymatic, microbial platform technology. It leads to major time savings, state of the art high throughput screening with 500,000 CPU (central processing unit) hours/year, high accuracy and consistency. They look for industrial/academic partners from chemical, pharma, food, home care, material industry for R&D cooperation, e.g. new synthetic routes to speciality/fine/pharmaceutical chemicals
They look for industrial/academic partners from the fields pharma, food and feed, chemistry, personal and home care as well as from materials for research and development cooperations. Therein the company provides enzyme technology solutions in the partner’s R&D projects regarding, for example, new synthetic routes towards specialty, fine and pharmaceutical chemicals. However, optimization of the partner’s existing processes, by the optimization and/or implementation of enzymes is also possible They are also open to other forms of cooperation.
Traditional ways to produce pharmaceuticals and other chemicals often require environmentally unfriendly reagents and harsh conditions, such as heavy metals, corrosive acids and high temperatures. Enzymes, functioning as proteins with green and excellent catalytic performance, offer efficient, eco-friendly and safe alternatives for traditional chemistry and can even significantly shorten synthetic routes. However, the industrial applicability of natural enzymes as biocatalysts is often restricted by, for example, their limited activity on unnatural substrates and instability at industrial process conditions, such as the necessity of organic co-solvents and high substrate loadings. A German-Sino company provides solutions which overcome the limitations of natural enzymes in industrial biocatalysis. The company provides an all-in-one R&D and commercialization service package spanning from first assessment of customer's needs to final industrial realization of developments. This whole process is guided by a team of highly experienced scientists from all over the world applying the latest state of the art technologies. With their extensive experience in directed enzyme evolution, strain engineering, fermentation process development and commercial-scale biocatalytic production, they successfully apply a proprietary R&D platform to develop novel, optimized enzyme technologies. This enzyme directed evolution platform is spearheaded by the integration of bioinformatic database guided design, computer modelling and simulations, as well as state of the art high throughput screening systems. Fields of application are fine chemical, pharmaceutical, food, personal and home care and material industries. They are also exploring the development of biocatalysis technology for feed, environmental and waste treatment industries. They look for industrial / academic partners from the fields mentioned above to offer enzyme technology solutions in the partner’s R&D projects regarding, for example, new synthetic routes towards specialty, fine and pharmaceutical chemicals. They also enable the optimization of the partner’s existing processes, by the optimization and/or implementation of enzymes. The company is also open to other forms of cooperation.
Advantages and innovations
The proprietary enzyme engineering platform of the German-sino SME is a combination of two Nobel prize winning technologies (directed evolution and computational enzyme engineering), with the following key advantages: - The application of bioinformatics-assisted design, simulations and analysis of protein mutations leads to major time savings and higher success rates within in the development of novel industrial enzymes. - State of the art high throughput screening technologies and a supercomputer account with 500,000 CPU (central processing unit) hours/year allow for time efficient and parallel handling of up to six computer aided enzyme evolution projects. - Automated and controlled laboratory procedures deliver higher accuracy and consistency of experimental results. - The created novel enzymes provide unpreceded performance in nature, meet industrial applicability criteria and generate new intellectual property. - The developed enzymatic processes have been proven to enable the manufacturing of diverse optically pure value-added products.
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