Multifunctional nanoparticles for the diagnosis and treatment of cancer
A research group from a major Spanish university has developed a synthesis method of polymeric multifunctionalized nanoparticles that have the ability to diagnose, treat and monitor different types of cancer. The group is looking for a pharmaceutical company interested in a license agreement of the patented technology.
The University is looking for a major pharmaceutical company or alternatively a company specialised in Nanotechnology. The company should have the capacity to develop functionalized nanoparticles.
Nowadays, functionalized nanoparticles are opening a wide range of opportunities to improve the diagnosis and treatment of different kind of pathologies. A research group from a major Spanish university has developed and patented functionalized nanoparticles that are focussed in the integration of diagnosis and therapy in one nanodevice, so called theragnosis. This approach enables the diagnosis together with the treatment and monitoring of the treatment efficiency and disease progress at the same time. The nanoparticles are conjugated with the following agents: • A tumour-specific ligand refers to any molecule, particularly any peptide, which is tumour-specific of the tumour to be treated or diagnosed. This ligand is conjugated to the surface of the nanoparticle. • An imaging tracker refers to any agent that can be used for monitoring the efficacy of the treatment or the diagnosis. • Drug/s to treat the tumour Unlike nanoparticles for theragnostic known in the prior art, where the drug and the imaging tracker are heterogeneously encapsulated inside the particle, the controlled multi-functionalization of these new nanoparticles allows tuning the ratio between the amounts of each one of the components: the drug, the ligand and the diagnostic agent. This fact increases dramatically the possibilities of developing more effective nanodevices for controlled released and monitoring in real time. The university is looking for a pharmaceutical company in order to reach a license agreement for the patented technology.
Advantages and innovations
Multifunctional tool: The nanoparticles allow the integration into a single therapeutic agent with the following abilities: - Diagnosis due to the imaging tracker - Treating cancer, thanks to the therapeutic payload - Monitoring the efficacy of the treatment Active tumour-targeting: The tumour-specific ligand increases the retention and accumulation of nanoparticles in the tumour resulting in an efficient and selective internalization in the tumour cells. This allows: - Improvement in the therapeutic efficacy. - Reduction of anticancer drug toxicity. Administering drugs locally rather than systemically (affecting the whole body) is a common way to decrease side effects. Versatile therapeutic agents: The nanoparticles can diagnose and treat different types of cancer by changing the imaging tracker and the drug respectively (personalized medicine). Stable nanoparticles with an efficient cancer cell internalization.
Under development/lab tested
Intellectual Property Rights (IPR)
Patent(s) applied for but not yet granted
Register your interest
How it works
- Tell us about yourself
- We’ll discuss with you
- We put the right partners in touch
EEN help you find the right partner, rather than you going it alone.
Our role is to review and collate the most suitable submissions, and then send them to the client who posted the opportunity. We consult with you, and the client, to make the process professional and easy.
These are live opportunities. Your registration of interest on the site is just like a professional approach to a business at a networking event. To stand the best chance of success, make your submission really sing. Sell why the client who posted the opportunity should work with you. Excite them. Ask questions. Try and avoid copy and pasting words from elsewhere.
Once the client has chosen their partner, we'll introduce them over email and keep in touch with both parties to see how it's going. Sometimes things progress quickly. Sometimes because of changing priorities for either party, things progress slowly, but you never know - your next big business break could start right here.
First we need to check you’re human.
Thank you for verifying your email. We have sent you a confirmation email containing a 6 digit verification code to unlock the form below