Partnering opportunity

Antigens for specific detection of antibodies against Coxiella burnetii, and some chlamydial and rickettsia species with practical use in agriculture, livestock production, slaughterhouses, milk production, animal skin-processing and veterinary industries

Summary

A Slovak institute has developed new highly purified corpuscular antigens of Coxiella burnetii, and some chlamydial and rickettsial species. They were designed for accurate measurement of antibodies against these bacteria in serum, plasma and milk samples of animals and humans. An efficient corpuscular vaccine for prophylaxis against coxiellosis in livestock is also available. These products are open for license and/or joint venture.

Partner sought

- Type of partner sought: The Slovak research institute is looking especially for these kind of partners: institutes and institutions - hospitals, health centres, veterinary institutes, regional veterinary stations, etc. - Field of activity: health, veterinary, agriculture - Role of partner: The research institute is looking for cooperation via joint venture agreement (the research institute has this specific technological project and is looking for a partner) or via license agreement (the research institute is offering a license).

Description

A Slovak institute active in virology and microbiology has developed new highly purified corpuscular antigens enabling rapid, simple, sensitive and specific detection of antibodies against Coxiella burnetii and some chlamydial and rickettsial species in serum, plasma and milk samples of animals and in human. Antigens are white or slightly yellow, uniformly turbid suspensions of highly purified bacterial cells in phosphate buffered saline with thiomersal or phenol as a preservative. However, a sediment may be formed after a longer period of storage it can easily be re-suspended by shaking. Here is the list of developed antigens: Antigens for Q fever serodiagnotics: Complement fixation (CF) test • Coxiella burnetii phase I antigen for CF test • Coxiella burnetii phase II antigen for CF test Enzyme-linked immunosorbent assay (ELISA) • Coxiella burnetii phase I antigen for ELISA test • Coxiella burnetii phase II antigen for ELISA test Antigens for chlamydiosis serodiagnotics Complement fixation (CF) test • Chlamydia psittaci antigen for CF test • Chlamydia abortus antigen for CF test Enzyme-linked immunosorbent assay (ELISA) • Chlamydia psittaci antigen for ELISA test • Chlamydia abortus antigen for ELISA test Antigens for spoted fever group rickettsiosis serodiagnotics Enzyme-linked immunosorbent assay (ELISA) • Rickettsia conorii antigen for ELISA test • Rickettsia akari antigen for ELISA test • Rickettsia slovaca antigen for ELISA test Potentialities of application of this technology: Professions at high exposition risk: personnel in agriculture, life stock production, slaughterhouses, milk production, animal skin-processing industry, veterinarians and laboratory personnel. The Slovak research institute is looking for cooperation via joint venture agreement (the partner for this specific technological project is sought) or via license agreement (the research institute is offering a license). These types of cooperation have been chosen because they are fitting todays need of the Slovak institute in the best possible way.

Advantages and innovations

Rapid antigen detection testing would allow a more rational use of antibiotics and would prevent adverse effects of antibiotics on the patient, antibiotic resistance emergence and the growth of inefficient health expense.

Development stage

Field tested/evaluated

Intellectual Property Rights (IPR)

Secret Know-how


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